| Shawnee St. Games/Schedule |
| Regular Season |
| Nov. 10, 2020 | Day 22 | Shawnee St. (6) - Ohio Christian | 96-62  |
| Nov. 13, 2020 | Day 25 | Grace Coll. - Shawnee St. (6) | 94-99 |
| Nov. 19, 2020 | Day 31 | Shawnee St. (6) - Life | 63-53 |
| Nov. 21, 2020 | Day 33 | Shawnee St. (6) - Great Lakes Chr. | 92-70 |
| Nov. 25, 2020 | Day 36 | Shawnee St. (6) - Rio Grande | 61-64  |
| Dec. 3, 2020 | Day 44 | Cumberland - Shawnee St. (6) | 68-57 |
| Dec. 5, 2020 | Day 46 | Lindsey Wilson - Shawnee St. (6) | 47-67 |
| Dec. 10, 2020 | Day 51 | Shawnee St. (6) - Martin Methodist | 83-54 |
| Dec. 18, 2020 | Day 59 | Shawnee St. (6) - MVNU | 82-62 |
| Dec. 31, 2020 | Day 67 | Shawnee St. (6) - Cumberlands (25) | 80-72 |
| Jan. 2, 2021 | Day 69 | Pikeville - Shawnee St. (6) | 79-91 |
| Jan. 4, 2021 | Day 70 | Shawnee St. (6) - Thomas More | 81-57 |
| Jan. 7, 2021 | Day 73 | Shawnee St. (6) - Georgetown, KY (15) | 74-73 |
| Jan. 9, 2021 | Day 75 | Shawnee St. (6) - Campbellsville | 106-86 |
| Jan. 14, 2021 | Day 79 | Bethel, TN - Shawnee St. (6) | 76-76 |
| Jan. 16, 2021 | Day 81 | FHU - Shawnee St. (6) | 76-80 |
| Jan. 21, 2021 | Day 86 | Shawnee St. (6) - Lindsey Wilson | 90-70 |
| Jan. 23, 2021 | Day 88 | Shawnee St. (6) - Cumberland | 82-54 |
| Jan. 25, 2021 | Day 90 | Shawnee St. (6) - Grace Christian | 102-69 |
| Jan. 28, 2021 | Day 93 | Martin Methodist - Shawnee St. (6) | 66-81 |
| Jan. 30, 2021 | Day 95 | Life - Shawnee St. (6) | 77-81 |
| Feb. 4, 2021 | Day 100 | Shawnee St. (6) - Pikeville | 101-90 |
| Feb. 6, 2021 | Day 102 | Cumberlands (25) - Shawnee St. (6) | 78-85 |
| Feb. 8, 2021 | Day 104 | Thomas More - Shawnee St. (6) | 68-77 |
| Feb. 20, 2021 | Day 116 | Campbellsville - Shawnee St. (6) | 54-86 |
| Feb. 28, 2021 | Day 123 | Shawnee St. (6) - Cumberland | 90-75 |
| Mar. 1, 2021 | Day 129 | Shawnee St. (6) - Martin Methodist | 91-82 |
| Mar. 2, 2021 | Day 130 | Shawnee St. (6) - Thomas More | 70-54 |
| Mar. 13, 2021 | Day 134 | Shawnee St. (6) - WVU Tech | 76-70 |
| 1/8 Finals |
| Mar. 18, 2021 | Day 135 | Shawnee St. (6) - Bethel, KS (18) | 69-59 |
| Quarter-Finals |
| Mar. 20, 2021 | Day 136 | Shawnee St. (6) - Jamestown | 76-65 |
| Final Four |
| Mar. 22, 2021 | Day 137 | St.Francis, IN (24) - Shawnee St. (6) | 77-82 |
| Finals |
| Mar. 23, 2021 | Day 138 | Shawnee St. (6) - LC State (4) | 74-68 |
