| Michigan St. Games/Schedule |
| Regular Season |
| Nov. 13, 2015 | Day 1 | Florida Atlantic - Michigan St. (2) | 55-82  |
| Nov. 17, 2015 | Day 5 | Kansas (1) - Michigan St. (2) | 73-79 |
| Nov. 20, 2015 | Day 8 | Ark.-Pine Bluff - Michigan St. (2) | 46-92 |
| Nov. 23, 2015 | Day 11 | E.Michigan - Michigan St. (2) | 65-89 |
| Nov. 26, 2015 | Day 14 | Boston Coll. - Michigan St. (2) | 68-99 |
| Nov. 27, 2015 | Day 15 | Boise St. - Michigan St. (2) | 67-77 |
| Nov. 29, 2015 | Day 17 | Michigan St. (2) - Providence | 77-64 |
| Dec. 2, 2015 | Day 20 | Louisville - Michigan St. (2) | 67-71 |
| Dec. 5, 2015 | Day 23 | Binghamton - Michigan St. (2) | 33-76 |
| Dec. 9, 2015 | Day 27 | Md-E Shore - Michigan St. (2) | 35-78 |
| Dec. 12, 2015 | Day 30 | Florida - Michigan St. (2) | 52-58 |
| Dec. 19, 2015 | Day 37 | Northeastern - Michigan St. (2) | 58-78 |
| Dec. 22, 2015 | Day 40 | Oakland - Michigan St. (2) | 93-99 |
| Dec. 29, 2015 | Day 46 | Iowa (24) - Michigan St. (2) | 83-70  |
| Jan. 2, 2016 | Day 50 | Minnesota - Michigan St. (2) | 61-69 |
| Jan. 7, 2016 | Day 55 | Michigan St. (2) - Illinois | 79-54 |
| Jan. 10, 2016 | Day 58 | Penn St. - Michigan St. (2) | 65-92 |
| Jan. 14, 2016 | Day 62 | Michigan St. (2) - Iowa (24) | 59-76 |
| Jan. 17, 2016 | Day 65 | Wisconsin - Michigan St. (2) | 77-76 |
| Jan. 20, 2016 | Day 68 | Michigan St. (2) - Nebraska | 71-72 |
| Jan. 23, 2016 | Day 71 | Michigan St. (2) - Maryland (17) | 74-65 |
| Jan. 28, 2016 | Day 76 | Northwestern - Michigan St. (2) | 45-76 |
| Jan. 31, 2016 | Day 79 | Michigan St. (2) - Rutgers | 96-62 |
| Feb. 6, 2016 | Day 85 | Michigan - Michigan St. (2) | 73-89 |
| Feb. 9, 2016 | Day 88 | Purdue (10) - Michigan St. (2) | 82-81 |
| Feb. 14, 2016 | Day 93 | Michigan St. (2) - Indiana (12) | 88-69 |
| Feb. 18, 2016 | Day 97 | Wisconsin - Michigan St. (2) | 57-69 |
| Feb. 23, 2016 | Day 102 | Michigan St. (2) - Ohio St. | 81-62 |
| Feb. 28, 2016 | Day 107 | Penn St. - Michigan St. (2) | 57-88 |
| Mar. 2, 2016 | Day 110 | Michigan St. (2) - Rutgers | 97-66 |
| Mar. 5, 2016 | Day 113 | Ohio St. - Michigan St. (2) | 76-91 |
| Conferences Tournaments |
| Mar. 11, 2016 | Day 119 | Ohio St. - Michigan St. (2) | 54-81 |
| Mar. 12, 2016 | Day 120 | Maryland (17) - Michigan St. (2) | 61-64 |
| Mar. 13, 2016 | Day 121 | Purdue (10) - Michigan St. (2) | 62-66 |
| National Tournament Day 1 |
| Mar. 18, 2016 | Day 4 | Middle Tenn.St. - Michigan St. (2) | 90-81 |
