| Michigan St. Games/Schedule |
| Regular Season |
| Nov. 3, 2025 | Day 1 | Colgate - Michigan St. (11) | 69-80  |
| Nov. 8, 2025 | Day 6 | Arkansas (16) - Michigan St. (11) | 66-69 |
| Nov. 13, 2025 | Day 11 | SJSU - Michigan St. (11) | 60-79 |
| Nov. 18, 2025 | Day 16 | Michigan St. (11) - Kentucky | 83-66 |
| Nov. 21, 2025 | Day 19 | Detroit - Michigan St. (11) | 56-84 |
| Nov. 25, 2025 | Day 23 | Michigan St. (11) - Ecuador | 89-56 |
| Nov. 27, 2025 | Day 25 | Michigan St. (11) - UNC (13) | 74-58 |
| Dec. 2, 2025 | Day 30 | Iowa - Michigan St. (11) | 52-71 |
| Dec. 6, 2025 | Day 34 | Duke (6) - Michigan St. (11) | 66-60  |
| Dec. 13, 2025 | Day 41 | Michigan St. (11) - Penn State | 76-72 |
| Dec. 16, 2025 | Day 44 | Toledo - Michigan St. (11) | 69-92 |
| Dec. 20, 2025 | Day 48 | Oakland - Michigan St. (11) | 70-79 |
| Dec. 29, 2025 | Day 54 | Cornell - Michigan St. (11) | 97-114 |
| Jan. 2, 2026 | Day 58 | Michigan St. (11) - Nebraska (8) | 56-58 |
| Jan. 5, 2026 | Day 61 | USC - Michigan St. (11) | 51-80 |
| Jan. 8, 2026 | Day 64 | Northwestern - Michigan St. (11) | 66-76 |
| Jan. 13, 2026 | Day 69 | Indiana - Michigan St. (11) | 60-81 |
| Jan. 17, 2026 | Day 73 | Michigan St. (11) - Washington | 80-63 |
| Jan. 20, 2026 | Day 76 | Michigan St. (11) - Oregon | 68-52 |
| Jan. 24, 2026 | Day 80 | Maryland - Michigan St. (11) | 48-91 |
| Jan. 27, 2026 | Day 83 | Michigan St. (11) - Rutgers | 88-79 |
| Jan. 30, 2026 | Day 86 | Michigan (4) - Michigan St. (11) | 83-71 |
| Feb. 4, 2026 | Day 91 | Michigan St. (11) - Minnesota | 73-76 |
| Feb. 7, 2026 | Day 94 | Illinois (12) - Michigan St. (11) | 82-85 |
| Feb. 13, 2026 | Day 100 | Michigan St. (11) - Wisconsin | 71-92 |
| Feb. 17, 2026 | Day 104 | UCLA - Michigan St. (11) | 59-82 |
| Feb. 22, 2026 | Day 109 | Ohio St. - Michigan St. (11) | 60-66 |
| Feb. 26, 2026 | Day 113 | Michigan St. (11) - Purdue (5) | 76-74 |
| Mar. 1, 2026 | Day 116 | Michigan St. (11) - Indiana | 77-64 |
| Mar. 5, 2026 | Day 120 | Rutgers - Michigan St. (11) | 87-91 |
| Mar. 8, 2026 | Day 123 | Michigan St. (11) - Michigan (4) | 80-90 |
| Mar. 13, 2026 | Day 124 | UCLA - Michigan St. (11) | 88-84 |
| National Tournament Day 1 |
| Mar. 19, 2026 | Day 1 | NDSU - Michigan St. (11) | 67-92 |
| National Tournament Day 2 |
| Mar. 21, 2026 | Day 1 | Louisville (19) - Michigan St. (11) | 69-77 |
| National Tournament Day 3 |
| Mar. 27, 2026 | Day 1 | Michigan St. (11) - UConn (3) | 63-67 |
