| Iowa St. Games/Schedule |
| Nov. 9, 2012 | Round 1 (Regular Season ) | Iowa St.-Southern | 82-59 |
| Nov. 12, 2012 | Round 4 (Regular Season ) | Iowa St.-Alabama A&M | 98-40 |
| Nov. 18, 2012 | Round 10 (Regular Season ) | Iowa St.-Campbell | 88-68 |
| Nov. 20, 2012 | Round 12 (Regular Season ) | Iowa St.-N.Carolina A&T | 86-57 |
| Nov. 23, 2012 | Round 15 (Regular Season ) | Cincinnati-Iowa St. | 78-70 |
| Nov. 24, 2012 | Round 16 (Regular Season ) | UNLV-Iowa St. | 82-70 |
| Dec. 1, 2012 | Round 23 (Regular Season ) | Iowa St.-BYU | 83-62 |
| Dec. 4, 2012 | Round 26 (Regular Season ) | Iowa St.-Florida Gulf Coast | 83-72 |
| Dec. 7, 2012 | Round 29 (Regular Season ) | Iowa-Iowa St. | 80-71 |
| Dec. 9, 2012 | Round 31 (Regular Season ) | Iowa St.-Nebraska-Omaha | 93-65 |
| Dec. 15, 2012 | Round 37 (Regular Season ) | Iowa St.-Drake | 86-77 |
| Dec. 19, 2012 | Round 41 (Regular Season ) | UMKC-Iowa St. | 61-76 |
| Jan. 1, 2013 | Round 52 (Regular Season ) | Iowa St.-Yale | 80-70 |
| Jan. 9, 2013 | Round 60 (Regular Season ) | Kansas-Iowa St. | 97-89 OT |
| Jan. 12, 2013 | Round 63 (Regular Season ) | Iowa St.-Texas | 82-62 |
| Jan. 16, 2013 | Round 67 (Regular Season ) | Iowa St.-W.Virginia | 69-67 |
| Jan. 19, 2013 | Round 70 (Regular Season ) | TCU-Iowa St. | 50-63 |
| Jan. 23, 2013 | Round 74 (Regular Season ) | Texas Tech-Iowa St. | 56-51 |
| Jan. 26, 2013 | Round 77 (Regular Season ) | Iowa St.-Kansas St. | 73-67 |
| Jan. 30, 2013 | Round 81 (Regular Season ) | Oklahoma St.-Iowa St. | 78-76 |
| Feb. 2, 2013 | Round 84 (Regular Season ) | Iowa St.-Baylor | 79-71 |
| Feb. 4, 2013 | Round 86 (Regular Season ) | Iowa St.-Oklahoma | 83-64 |
| Feb. 9, 2013 | Round 91 (Regular Season ) | Kansas St.-Iowa St. | 79-70 |
| Feb. 13, 2013 | Round 95 (Regular Season ) | Texas-Iowa St. | 89-86 OT |
| Feb. 16, 2013 | Round 98 (Regular Season ) | Iowa St.-TCU | 87-53 |
| Feb. 20, 2013 | Round 102 (Regular Season ) | Baylor-Iowa St. | 82-87 |
| Feb. 23, 2013 | Round 105 (Regular Season ) | Iowa St.-Texas Tech | 86-66 |
| Feb. 25, 2013 | Round 107 (Regular Season ) | Iowa St.-Kansas | 96-108 OT |
| Mar. 2, 2013 | Round 112 (Regular Season ) | Oklahoma-Iowa St. | 86-69 |
| Mar. 6, 2013 | Round 116 (Regular Season ) | Iowa St.-Oklahoma St. | 87-76 |
| Mar. 9, 2013 | Round 119 (Regular Season ) | W.Virginia-Iowa St. | 74-83 |
| Mar. 14, 2013 | Round 124 (Regular Season ) | Oklahoma-Iowa St. | 66-73 |
| Mar. 15, 2013 | Round 125 (Regular Season ) | Kansas-Iowa St. | 88-73 |
| Mar. 22, 2013 | Round 129 (National Tournament Round 2 ) | Notre Dame-Iowa St. | 58-76 |
| Mar. 24, 2013 | Round 130 (National Tournament Round 3 ) | Iowa St.-Ohio St. | 75-78 |
