NAIA League Games/Schedule (2021-2022)
| Holy Cross Coll. Games/Schedule | |||||||
| Regular Season | |||||||
| Oct. 21, 2021 | Day 8 | Lake Michigan - Holy Cross Coll. | 52-63  | ||||
| Oct. 25, 2021 | Day 12 | Andrews - Holy Cross Coll. | 45-65 | ||||
| Nov. 2, 2021 | Day 20 | East-West - Holy Cross Coll. | 64-66 | ||||
| Nov. 6, 2021 | Day 24 | Holy Cross Coll. - Bethel, IN | 93-80 | ||||
| Nov. 9, 2021 | Day 27 | Holy Cross Coll. - IU S.Bend (19) | 46-79  | ||||
| Nov. 12, 2021 | Day 30 | St.Mary of the Woods - Holy Cross Coll. | 47-65 | ||||
| Nov. 13, 2021 | Day 31 | Simmons Coll. - Holy Cross Coll. | 60-67 | ||||
| Nov. 17, 2021 | Day 35 | Holy Cross Coll. - GSU | 74-65 | ||||
| Nov. 20, 2021 | Day 38 | Judson - Holy Cross Coll. | 60-55 | ||||
| Nov. 23, 2021 | Day 41 | Holy Cross Coll. - Trinity Christian | 84-71 | ||||
| Dec. 1, 2021 | Day 48 | Roosevelt - Holy Cross Coll. | 64-57 | ||||
| Dec. 8, 2021 | Day 55 | SHU - Holy Cross Coll. | 62-60 | ||||
| Dec. 11, 2021 | Day 58 | St.Francis, IL - Holy Cross Coll. | 66-56 | ||||
| Dec. 15, 2021 | Day 62 | St.Xavier - Holy Cross Coll. | 60-51 | ||||
| Dec. 18, 2021 | Day 65 | Cardinal Stritch - Holy Cross Coll. | 62-82 | ||||
| Dec. 28, 2021 | Day 71 | Holy Cross Coll. - St.Francis, IN (16) | 52-77 | ||||
| Jan. 5, 2022 | Day 79 | Holy Cross Coll. - Judson | 56-68 | ||||
| Jan. 12, 2022 | Day 86 | Trinity Christian - Holy Cross Coll. | 69-64 | ||||
| Jan. 15, 2022 | Day 89 | Holy Cross Coll. - Cardinal Stritch | 66-64 | ||||
| Jan. 17, 2022 | Day 91 | IU S.Bend (19) - Holy Cross Coll. | 83-50 | ||||
| Jan. 19, 2022 | Day 93 | Calumet - Holy Cross Coll. | 58-84 | ||||
| Jan. 22, 2022 | Day 96 | Holy Cross Coll. - ONU | 64-100 | ||||
| Jan. 26, 2022 | Day 100 | Holy Cross Coll. - Roosevelt | 67-68 | ||||
| Jan. 29, 2022 | Day 103 | IU Northwest - Holy Cross Coll. | 77-72 | ||||
| Feb. 5, 2022 | Day 110 | GSU - Holy Cross Coll. | 75-80 | ||||
| Feb. 7, 2022 | Day 112 | Holy Cross Coll. - Lincoln | 53-79 | ||||
| Feb. 9, 2022 | Day 114 | Holy Cross Coll. - St.Francis, IL | 52-73 | ||||
| Feb. 12, 2022 | Day 117 | Holy Cross Coll. - St.Ambrose | 86-73 | ||||
| Feb. 14, 2022 | Day 119 | Holy Cross Coll. - St.Xavier | 63-69 | ||||
| Feb. 19, 2022 | Day 124 | TIU - Holy Cross Coll. | 56-59 | ||||
